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Phase 2 Trial Results: Weight Loss Outcomes in Type 2 Diabetes At the highest 12 mg dose, adults with type 2 diabetes achieved approximately 16.9% mean body weight reduction from baseline at 24 weeks in a randomised, placebo-controlled phase 2 trial published in The Lancet (2023)

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In this trial, 17,604 patients were enrolled to receive semaglutide 2.4 mg weekly or placebo and followed for approximately 36 months